At the University of California, scientists helped the fight against alcoholism by plying hundreds of thousands of worms with alcohol. They succeeded in finding the gene responsible for drunkenness in worms and hope this will help the study of alcoholism in people.
The alcohol seemed to affect the worms much like humans: " The drunken worms moved slower and more awkwardly than sober ones, and laid fewer eggs." However, as neurobiology professor Steven Treistman of the University of Massachusetts Medical School commented, "'Humans are a lot more complicated than the worm." Source